Increased secreted frizzled-related protein 4 and ficolin-3 levels in gestational diabetes mellitus women
نویسندگان
چکیده
منابع مشابه
Computer aided screening of secreted frizzled-related protein 4 (SFRP4): a potential control for diabetes mellitus.
Diabetes mellitus is a life threatening disease and scientists are doing their best to find a cost effective and permanent treatment of this malady. The recent trend is to control the disease by target base inhibiting of enzymes or proteins. Secreted frizzled-related protein 4 (SFRP4) is found to cause five times more risk of diabetes when expressed above average levels. This study was therefor...
متن کاملFicolin‐3/adiponectin ratio for the prediction of gestational diabetes mellitus in pregnant women
AIMS/INTRODUCTION To establish that the ficolin-3/adiponectin ratio is a predictor for gestational diabetes mellitus (GDM) and is eligible for screening tests for GDM. MATERIALS AND METHODS A prospective cohort study of 86 pregnant women who developed GDM and 273 normal glucose tolerance participants was carried out. Maternal serum ficolin-3, adiponectin levels were investigated at 16-18 week...
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objective: the role of wnt signaling and its antagonist; secreted frizzled related protein type 4 (sfpr4) was reported in rodent ovarian follicular development. this study examines immunolocalization of sfrp4 in ovaries of polycystic ovary (pco) rat model and evaluates its role in follicular growth arrest and its premature differentiation. materials and mathods: pco was induced with daily admin...
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A plethora of candidate genes have been identified for complex polygenic disorders, but the underlying disease mechanisms remain largely unknown. We explored the pathophysiology of type 2 diabetes (T2D) by analyzing global gene expression in human pancreatic islets. A group of coexpressed genes (module), enriched for interleukin-1-related genes, was associated with T2D and reduced insulin secre...
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ژورنال
عنوان ژورنال: Endocrine Journal
سال: 2018
ISSN: 0918-8959,1348-4540
DOI: 10.1507/endocrj.ej17-0508